发明名称 Desoxycyclodepsipetide
摘要 The invention relates to novel desoxycyclodepsipeptides of formula (I) in which C=X<1>, C=X<2>, C=X<3> and C=X<4> independently of each other respectively represent one of the CO, CS or CH2 groups, with at least one of these groups representing CH2. The invention also relates to their mixtures and derivatives. Said compounds are produced from cyclodepsipeptides having 24 ring members formed by alternating alpha -amino carboxylic acids and alpha -hydroxy carboxylic acids by complete or partial chemoselective reduction of the carbonyl groups of the amide function into methylene groups, using suitable reduction methods. The desoxycyclodepsipeptides produced according to the invention have an anthelmintic effect.
申请公布号 DE19810017(A1) 申请公布日期 1998.12.10
申请号 DE19981010017 申请日期 1998.03.09
申请人 BAYER AG, 51373 LEVERKUSEN, DE 发明人 DYKER, HUBERT, DR.-CHEM., 51065 KOELN, DE;SCHERKENBECK, JUERGEN, DR.-CHEM., 42929 WERMELSKIRCHEN, DE;HARDER, ACHIM, DR., 51109 KOELN, DE;MENCKE, NORBERT, DR., 51381 LEVERKUSEN, DE;SAMSON-HIMMELSTJERNA, GEORG VON, DR., 30625 HANNOVER, DE
分类号 C07D273/00;C07D413/10;C07D413/14;(IPC1-7):C07K11/02;A61K38/15 主分类号 C07D273/00
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