METHOD OF PREPARING 3-(2-[4-6-FLUOROBENZO [d] ISOXAZOL-3- YL] PIPERIDINE-1-Y) EHTYL-2-METHYL-6,7,8,9-TETRAHYDRY-4H- PYRIDO [1,2-a] PYRIMIDIN-4-ONE AND INTERMEDIATE COMPOUNDS FOR PREPARING THEREOF

摘要

FIELD: chemical industry. SUBSTANCE: method comprises reacting 3-(2- aminoethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido [1,2-a] pyrimidin-4-one (II) with isoxazole derivative of formula III wherein Y and Z are removable groups such as halogen or alkyl-or arylsulfonyloxy group in the presence of suitable solvent and base. The method makes it possible to simplify process for preparation of compound (I) due to using more readily available reagents. The present invention also describes compounds II and III. EFFECT: more efficient preparation method. 8 cl, 8 ex