NOVEL LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE

摘要

DNA and polypeptide sequences of a human lysophosphatidic acid acyltransferase (LPAAT) are disclosed. Methods and materials for production of LPAAT-1 and fragments and analogs thereof, production of antibodies, assays for identifying modulators of LPAAT and pharmaceutical compositions comprising LPAAT, polypeptides or modulators of LPAAT are provided. Also provided are methods for detecting LPAAT and lysophosphatidic acid.