| 发明名称 |
SPIRO-AZACYCLIC DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS |
| 摘要 |
Substituted spiro-azacyclic derivatives of structural formula (I) are tachykinin receptor antagonists of use, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
|
| 申请公布号 |
CA2289037(A1) |
申请公布日期 |
1998.12.03 |
| 申请号 |
CA19982289037 |
申请日期 |
1998.05.27 |
| 申请人 |
MERCK SHARP & DOHME LIMITED |
发明人 |
RAUBO, PIOTR ANTONI;KULAGOWSKI, JANUSZ JOZEF;SWAIN, CHRISTOPHER JOHN;THOMSON, CHRISTOPHER GEORGE |
| 分类号 |
A61P25/04;A61K31/438;A61K31/44;A61K31/444;A61K31/497;A61K31/501;A61K31/506;A61K31/53;A61P1/04;A61P1/08;A61P9/10;A61P11/00;A61P13/10;A61P17/00;A61P25/06;A61P29/00;A61P35/00;A61P43/00;C07D491/10;C07D491/107;(IPC1-7):C07D491/10;A61K31/435 |
主分类号 |
A61P25/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
