发明名称 |
COMBINED PRODUCT ASSOCIATING A NUCLEIC ACID WITH A SUBSTANCE BREAKING UP THE EXTRACELLULAR MATRIX FOR GENE THERAPY |
摘要 |
The invention concerns a combined product comprising at least a substance breaking up a cell extracellular matrix and at least a nucleic acid of interest, to be administered simultaneously, consecutively or spread over time, said nucleic acid being carried by an infectious viral particle or in the form of a synthetic vector. The invention also concerns the use of said product for therapeutic or vaccine purposes to prepare a medicine for treating the human or animal body using gene therapy and the use of a substance breaking up the extracellular matrix to improve the transfer and/or the expression of said nucleic acid of interest in a host cell or organism.
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申请公布号 |
WO9853853(A1) |
申请公布日期 |
1998.12.03 |
申请号 |
WO1998FR01084 |
申请日期 |
1998.05.29 |
申请人 |
TRANSGENE S.A.;ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES;BRAUN, SERGE |
发明人 |
BRAUN, SERGE |
分类号 |
A61K31/7088;A61K35/76;A61K38/46;A61K45/00;A61K48/00;C12N15/87;(IPC1-7):A61K48/00 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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