发明名称 THE USE OF A NITROXIDE OR A PRODRUG THEREOF IN THE PROPHYLACTIC AND THERAPEUTIC TREATMENT OF CANCER
摘要 The present invention provides a method for the prophylactic and therapeutic treatment of cancer. The method comprises administering to an animal, preferably a mammal, more preferably a human, at risk for developing a cancer or having a cancer a nitroxide or a prodrug thereof, wherein the nitroxide or prodrug thereof preferably is alicyclic or heterocyclic and more preferably is a compound of Formula (I) or Formula (II): in an amount sufficient to prevent or treat said cancer, wherein said cancer is susceptible to prevention or treatment by said nitroxide or prodrug thereof. Also provided is a composition for use in the method.
申请公布号 WO9853835(A1) 申请公布日期 1998.12.03
申请号 WO1998US10685 申请日期 1998.05.27
申请人 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;MITCHELL, JAMES, B.;RUSSO, ANGELO;DELUCA, ANNE, MARIE;CHERUKURI, MURALI, KRISHNA 发明人 MITCHELL, JAMES, B.;RUSSO, ANGELO;DELUCA, ANNE, MARIE;CHERUKURI, MURALI, KRISHNA
分类号 C07D211/94;A61K31/445;A61K33/00;A61P35/00;(IPC1-7):A61K33/00;A61K31/395;A61K49/00 主分类号 C07D211/94
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