| 发明名称 |
SELECTIVE INDUCTION OF CELL DEATH BY DELIVERY OF AMINO-TERMINAL INTERLEUKIN-1-ALPHA PRO-PIECE POLYPEPTIDE |
| 摘要 |
The present invention is directed to compositions and methods for selective induction of apoptosis in cancer cells, particularly malignant cancer cells, by delivery of an IL-1.alpha. propiece polypeptide (e.g., a native IL-1.alpha. propiece polypeptide, including IL-1.alpha. propiece polypeptide variant) to a cancer cell.
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| 申请公布号 |
CA2288967(A1) |
申请公布日期 |
1998.12.03 |
| 申请号 |
CA19982288967 |
申请日期 |
1998.05.28 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
POLLOCK, ALLAN S.;TURCK, JOHANNA;LOVETT, DAVID H. |
| 分类号 |
C12N15/09;A61K38/00;A61K38/16;A61K38/17;A61P35/00;A61P43/00;C07K1/00;C07K14/545;C09H3/00;C12N5/10;(IPC1-7):C07K1/00 |
主分类号 |
C12N15/09 |
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