| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject tablet which disintegrates rapidly so as to allow chitosan to easily disintegrate in the stomach, by including sodium chloride as a disintegrating agent. SOLUTION: This tablet is obtained by including 20-60 wt.% chitosan, 0.5-5 wt.%, preferably 2-4 wt.%, sodium chloride as a disintegrating agent, and, if necessary, mineral-containing ingredient(s), extract(s) from animal/plant, vitamin(s), oligosaccharide(s), pharmaceutically active ingredient(s), and so on, adding additive(s) such as a vehicle, lubricant, coloring agent, taste-conditioning agent, and odor-conditioning agent, followed by conducting a commonly used compression. Chitosan in the tablet disintegrates in the stomach, and gels due to pH increase in the intestine, and the resultant gel incorporates fats to give a dieting effect. |
