| 发明名称 |
OLIGONUCLEOTIDE ANALOGUES WITH TERMINAL 3'-3' OR 5'-5'- -INTERNUCLEOTIDE LINKAGES, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEM CONTAINING |
| 摘要 |
<p>Therapeutically utilisable oligonucleotides of the formulae (I) and (II), whereof substituents' meanings are described in the Claims, are obtained by introducing terminal 3'-3'- or 5'-5'- linkages. These nuclease-stable compounds suppress the biological function of nucleic acids.</p> |
| 申请公布号 |
SK279544(B6) |
申请公布日期 |
1998.12.02 |
| 申请号 |
SK19910002014 |
申请日期 |
1991.07.01 |
| 申请人 |
ROSCH HANNELORE;FROHLICH ANJA;RAMALHO-ORTIGAO JOSE F.;MONTENARH MATTHIAS;SELIGER HARTMUT |
发明人 |
ROSCH HANNELORE;FROHLICH ANJA;RAMALHO-ORTIGAO JOSE F.;MONTENARH MATTHIAS;SELIGER HARTMUT |
| 分类号 |
A61K31/70;A61K31/7052;A61P31/12;A61P35/00;C07H19/10;C07H19/20;C07H21/00;C07H21/04;C12N15/00;C12N15/09;C12Q1/68;G01R15/18;(IPC1-7):C07H21/00 |
主分类号 |
A61K31/70 |
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