1,4-dihydropyridine compound and pharmaceutical composition containing the same

摘要

PCT No. PCT/JP95/01507 Sec. 371 Date Jun. 4, 1997 Sec. 102(e) Date Jun. 4, 1997 PCT Filed Jul. 28, 1995 PCT Pub. No. WO96/04268 PCT Pub. Date Feb. 15, 1996A 1,4-dihydropyridine compound having the formula (I): <IMAGE> (I) wherein, R1 indicates -COO-A-(3-pyridyl), A indicates a C3-C6 straight chain alkylene group in which one piperazine may be interposed; R2 indicates a C2-C10 alkyl group, alkenyl group or alkynyl group; a lower alkyl group or lower alkenyl group having a substituent; or a cycloalkyl group which may have a substituent; R3 indicates the same group as R1 or -COO-R4; and R4 indicates a lower alkyl group which may have a substituent or its pharmacologically acceptable salt and an anti-allergenic drug, antiphlogistic, drug for overcoming resistance to anti-cancer drugs, or drug for reinforcing the effect of anti-cancer drugs containing the same as effective ingredients.