| 发明名称 |
Protein kinase C inhibitors |
| 摘要 |
This invention provides novel bis-indolemaleimide macrocycle derivatives of the formula: <IMAGE> The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.
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| 申请公布号 |
US5843935(A) |
申请公布日期 |
1998.12.01 |
| 申请号 |
US19970903236 |
申请日期 |
1997.07.12 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
HEATH, JR., WILLIAM F.;JIROUSEK, MICHAEL R.;MCDONALD, III, JOHN H.;RITO, CHRISTOPHER J. |
| 分类号 |
C07D487/14;A61K31/395;A61K31/40;A61K31/407;A61K31/55;A61P3/08;A61P3/10;A61P9/00;A61P9/10;A61P17/00;A61P25/00;A61P29/00;A61P35/00;A61P43/00;C07C43/174;C07C43/178;C07D487/22;C07D491/147;C07D491/22;C07D498/22;C07D513/22;C07F7/18;(IPC1-7):A61K31/55 |
主分类号 |
C07D487/14 |
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