Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient

摘要

A thiazolidinone compound represented by general formula (I) or a pharmacoligically acceptable salt thereof, <IMAGE> (I) wherein W represents sulfur or oxygen and X represents -N(R1)-, or alternatively X represents sulfur or oxygen and W represents -N(R1)-, and R1 represents hydrogen, alkyl or substituted alkyl; R2 and R3 are the same or different from each other, and each represents hydrogen, alkyl, substituted alkyl, aryl, or 5- or 6-membered heteroaryl; R4 represents hydrogen, alkyl or substituted C1-C4 alkyl; R5 represents substituted cycloalkyl which may contain nitrogen, provided the substituents include -B-ONO2 (wherein B represents a single bond or alkylene) as the indispensable member and alkyl groups as optional members; and A represents a single bond or alkylene, has an excellent anti-anginal effect and thus is useful as an angina pectoris remedy or preventive.