Sindbis virus expression system for recombinant antibody production

摘要

This invention provides a method of expressing a multimeric polypeptide. This invention also provides a method of expressing biologically active recombinant antibodies. This invention also provides an expression cell line capable of producing multimeric polypeptides or biologically active recombinant antibodies. This invention also provides methods of producing biologically active recombinant antibodies or multimeric polypeptides. This invention also provides a transgenic animal comprising the expression cell line capable of producing biologically active recombinant antibodies or multimeric polypeptides. Also, this invention provides a method for preventing infectious diseases associated with arthropods.