| 发明名称 |
Diphtheria toxin receptor-binding region |
| 摘要 |
The invention features a polypeptide consisting of amino acids 379-535 of diphtheria toxin, and portions thereof. This region, shown by X-ray crystallographic analysis to comprise the receptor binding domain of diphtheria toxin, is used as an immunogen and clinical therapeutic against diphtheria.
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| 申请公布号 |
US5843711(A) |
申请公布日期 |
1998.12.01 |
| 申请号 |
US19950552248 |
申请日期 |
1995.11.02 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
COLLIER, R. JOHN;EISENBERG, DAVID;FU, HAIAN;CHOE, SEUNGHYON |
| 分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/05;A61P31/04;C07H21/04;C07K1/02;C07K1/12;C07K14/195;C07K14/34;C07K14/41;C07K19/00;C12N1/21;C12P21/02;C12R1/19;(IPC1-7):C12N15/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
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