发明名称 |
Substituted N-arylmethyl and heterocyclylmethyl-1H-pyrazolo (3,4-b) quinolin-4-amines and compositions and methods of use thereof |
摘要 |
Substituted N-arylmethyl and heterocyclylmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines, pharmaceutical compositions containing them and methods for a) effecting c-GMP-phosphodiesterase inhibition, b) treating heart failure and/or hypertension, c) reversing or reducing nitrate-induced tolerance and d) treating angina pectoris, congestive heart disease and myocardial infarction utilizing them.
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申请公布号 |
US5843956(A) |
申请公布日期 |
1998.12.01 |
申请号 |
US19970801679 |
申请日期 |
1997.02.18 |
申请人 |
SANOFI |
发明人 |
KUMAR, VIRENDRA;DORITY, JR., JOHN ALAN |
分类号 |
A61K31/435;A61K31/4745;A61P9/00;A61P9/12;C07D471/04;(IPC1-7):A61K31/47;A61K31/495;C07D215/46 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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