| 摘要 |
<p>The invention relates to indole derivatives having theformulaThese compounds are useful psychotherapeutical means and activeserotonin (5-HT) antagonists and can be used for the treatment ofdepression, fear conditions, digestive impairements, obessity,drug abuse, headaches, migraine, pains, chronic pains with fits inhalf of the cranial region and hadache related to vascularimpairements, and other disorders arising from insufficientserotonenergic neurotransmission. The compounds are also used asantihypertensive and vasodilator means affecting the centralnervous system. The invention also relates to methods andintermediate compounds for their preparation, to pharmaceuticalcompositions containing the active compounds and to theirapplication.28 claims</p> |
