METHOD OF DRUG PARTICLE PREPARING

摘要

FIELD: pharmaceutical technology. SUBSTANCE: method involves milling a drug in the presence of solid milling medium. A solid milling medium is polymeric resin (density is 0.8-3.0 g/cm ) as particles of an average size 0.1-3 mm. Polystyrene cross-linked with divinylbenzene or polycarbonate are used as polymeric resin. Diagnostic contrast image agent, for example, ethyl-3,5-bis-acetamido-2,4,6-triiodobenzoate is used as a drug. EFFECT: decreased content of polluting impurities in medicinal particles. 11 cl, 6 exi