BISARYL COMPOUNDS AND CANCER REMEDIES CONTAINING THE SAME

摘要

Cancer remedies, each containing a compound of the following general formula (I): Ar1-S-R1-S-Ar2 ¢wherein RP represents a non-metallic connecting group; Ar1 and Ar2 each independently represents aryl or heteroaryl having 1 to 3 hydroxyls which may be substituted with a monovalent group on the ring thereof (and optionally having 1 to 3 substituents other than the hydroxyl on the ring thereof)! or a physiologically acceptable salt thereof; and compounds of the following general formula (XII): Ar23-S-R22-N(R24)-R23-S-Ar24 ¢wherein R22 and R23 each independently represents a divalent group; R24 represents a monovalent group or atom, or R24 may be bonded to R22 and/or R23 to form a cyclic structure and further bonded to one or two C1-4 alkylene groups to form a divalent group; and Ar23 and Ar24 each independently represents aryl or heteroaryl (optionally having 1 to 3 substituents other than hydroxyl on the ring thereof) having 1 to 3 hydroxyls which may be substituted with a monovalent group; excluding specified compounds! and salts thereof.