发明名称 METHODS FOR TREATMENT OF CONDITIONS ASSOCIATED WITH LACTOSYLCERAMIDE
摘要 The present invention includes methods for treatment and prophylaxis of diseases, post-surgical disorders and bacterial infections associated with lactosylceramide. The methods generally provide for administration for a mammal, particularly a human, of a therapeutically effective amount of a compound that inhibits UDPGal:GlcCer.beta.1-4 galactosylceramide (GalT-2). In vitro and in vivo assays for detecting compounds with therapeutic capacity to modulate GalT-2 are also provided.
申请公布号 CA2290742(A1) 申请公布日期 1998.11.26
申请号 CA19982290742 申请日期 1998.05.14
申请人 JOHNS HOPKINS UNIVERSITY 发明人 CHATTERJEE, SUBROTO
分类号 C07D295/12;A61K31/16;A61K31/40;A61K31/4453;A61K31/5375;A61K45/00;A61P9/08;A61P9/10;A61P17/02;A61P29/00;A61P31/04;A61P35/00;A61P43/00;(IPC1-7):A61K31/16;A61K31/445;A61K31/535 主分类号 C07D295/12
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