| 摘要 |
<p>In the last two decades biosensors have been developed for specific applications (industrial, biomedical or environmental, etc) and they are becoming competitive with respect to conventional analytic technologies. Yet, these equipments which are essentially based on the retention of micro-organisms in membranes have inherent limitations. There are two fundamental innovations to today's technology: (a) continuous availability of micro-organisms when using a chemostat, thus providing for the monitoring of high toxicity samples when disposing the used micro-organisms after each determination; (b) the physical membrane of separation between the medium to be analysed and the transducer is removed thereby providing for the amplification of the linearity range of the signal and reducing noticeably the time necessary to obtain a stable signal. The invention discloses a biosensor system for on-line monitoring of chemical substances contained in fluids. An example of applications is the use of the system to on-line determination of the oxygen biochemical demand in water.</p> |
