发明名称 |
2,3-DIHYDROBENZOFURAN DERIVATIVES |
摘要 |
2,3-Dihydrobenzofuran derivatives represented by general formula (1), optically active isomers thereof, or pharmacologically acceptable salts of these, wherein R1 represents hydrogen or acyl; R2, R3, and R4 each represents hydrogen, lower alkyl, or lower alkenyl; and R5 and R6 each represents hydrogen or optionally substituted alkyl, or R5 and R6 in combination represent cycloalkyl or a saturated heterocycle containing one or more oxygen atoms or alkyl-substituted nitrogen; provided that not both of R2 and R3 are t-butyl. The compounds are useful as remedial or preventive agents for various kidney diseases and as organ preservatives.
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申请公布号 |
WO9852557(A1) |
申请公布日期 |
1998.11.26 |
申请号 |
WO1998JP02248 |
申请日期 |
1998.05.22 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;ISHIKAWA, AKIRA;KATO, YOSHIAKI;TAMURA, KUNIO;TAKASHIMA, YOSHIAKI;CYNSHI, OSAMU |
发明人 |
ISHIKAWA, AKIRA;KATO, YOSHIAKI;TAMURA, KUNIO;TAKASHIMA, YOSHIAKI;CYNSHI, OSAMU |
分类号 |
A61K31/343;C07D307/79;C07D307/94;(IPC1-7):A61K31/34 |
主分类号 |
A61K31/343 |
代理机构 |
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代理人 |
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地址 |
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