PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS

摘要

Formation of cerebral amyloid associated with Alzheimer's disease can be treated or averted using medicaments that are effective in vivo in preventing disruption of dense microspheres (DMS) or in altering the disruption so as to (i) reduce the volume of tissue occupied by redistributed, transformed DMS protein material and its associated injury focus; (ii) reduce the persistence or duration of injury and inflammation associated with the disrupted DMS and redistributed transformed DMS protein material; and/or (iii) increase the digestion and removal of DMS material through the reticuloendothelial system.