NEW ECHINOCANDIDE DERIVATIVES WITH ANTIMICROBIAL ACTIVITY

摘要

The invention relates to new polypeptide compounds represented by formula (I), wherein R<1> is hydrogen, etc., R<2> is hydrogen, etc., R<3> is hydrogen, etc., and R<4> is hydrogen, etc., or a salt thereof which have antimicrobial activities (especially antifungal activities), inhibitory activity on beta -1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia in a human being or an animal.