| 发明名称 |
Methods of use of chimerized, humanized, and single chain antibodies specific to VEGF receptors |
| 摘要 |
Monoclonal antibodies that specifically bind to an extracellular domain of a VEGF receptor and neutralize activation of the receptor are provided. In vitro and in vivo methods of using these antibodies are also provided.
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| 申请公布号 |
US5840301(A) |
申请公布日期 |
1998.11.24 |
| 申请号 |
US19940326552 |
申请日期 |
1994.10.20 |
| 申请人 |
IMCLONE SYSTEMS INCORPORATED |
发明人 |
ROCKWELL, PATRICIA;GOLDSTEIN, NEIL I. |
| 分类号 |
A61K31/337;A61K38/00;A61K39/395;A61K45/06;A61K49/00;A61K51/10;C07H21/00;C07K14/485;C07K14/71;C07K16/18;C07K16/22;C07K16/28;C12N5/18;C12N5/20;C12N15/13;C12P21/08;(IPC1-7):A61K39/395;C07K16/00 |
主分类号 |
A61K31/337 |
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