发明名称 |
A process for the synthesis of modified p-chiral nucleotide analogues |
摘要 |
The process of the instant invention is drawn to the synthesis of modified P-chiral nucleotide analogues in the form of pure diastereomers possessing preselected configuration at the P-atom. Oligonucleotides prepared by the method of the invention containing P-chiral compounds have enhanced hybridization and transporting properties. |
申请公布号 |
AU6934398(A) |
申请公布日期 |
1998.11.24 |
申请号 |
AU19980069343 |
申请日期 |
1998.04.23 |
申请人 |
POLSKA AKADEMIA NAUK CENTRUM BADAN MOLEKULARNYCH I MAKROMOLEKUL |
发明人 |
WOJCIECH J. STEC;LUCYNA A. WOZNIAK;ARKADIUSZ CHWOROS;JAROS;M(D)AW PYZOWSKI |
分类号 |
C07H21/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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