发明名称 |
Ingap protein involved in pancreatic islet neogenesis |
摘要 |
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display technique a cDNA clone expressed in cellophane wrapped but not in control pancreata was identified. Using this cDNA as a probe, a cDNA library was screened and a gene not previously described was identified and named INGAP.
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申请公布号 |
US5840531(A) |
申请公布日期 |
1998.11.24 |
申请号 |
US19960709662 |
申请日期 |
1996.09.09 |
申请人 |
MOGILL UNIVERSITY;EASTERN VIRGINIA MEDICAL SCHOOL OF THE MEDICINE COLLEGE OF HAMPTON ROADS |
发明人 |
VINIK, AARON I.;PITTENGER, GARY L.;RAFAELOFF, RONIT;ROSENBERG, LAWRENCE;DUGUID, WILLIAM P. |
分类号 |
A01K67/027;A61K31/70;A61K38/00;A61K39/395;A61K48/00;A61P1/00;A61P3/08;A61P43/00;C07K14/47;C07K14/52;C07K16/24;C12N5/10;C12N15/02;C12N15/09;C12P21/08;C12Q1/68;G01N33/53;G01N33/566;(IPC1-7):C12N15/00 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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