发明名称 4-aminomethyl-1-azaadamantane derived benzamides
摘要 This invention relates to compounds of the formula: <IMAGE> or a pharmaceutically acceptable salt thereof wherein Z is selected from the group consisting of <IMAGE> R1 is alkoxy of one to six carbon atoms; R2, R3, R4 and R5 are the same or different and are selected from the group consisting of hydrogen, halogen, CF3, hydroxy, alkoxy of one to six carbon atoms, acyl of two to seven carbon atoms, amino, amino substituted by one or two alkyl groups of one to six carbon atoms, C2-C7 acylamino, aminocarbonyl, aminosulfone optionally substituted by one or two alkyl groups of one to six carbon atoms, C1-C6 alkylsulfone and nitro; m is 1 or 2; X is O or NR7; and R7 is hydrogen or alkyl of 1 to 6 carbon atoms.
申请公布号 US5840903(A) 申请公布日期 1998.11.24
申请号 US19920919679 申请日期 1992.07.27
申请人 G. D. SEARLE & CO. 发明人 FLYNN, DANIEL LEE;SHONE, ROBERT L.
分类号 A61K31/435;A61P1/04;A61P1/08;A61P1/12;A61P1/14;A61P25/04;A61P25/20;A61P25/22;A61P25/28;A61P43/00;C07D471/18;(IPC1-7):A61K31/44;C07D451/00;C07D221/02 主分类号 A61K31/435
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