发明名称 COMPLEX SALT OF HEMATOPORPHYRINE AND DERIVATIVES THEREOF, MIXTURE OF COMPLEX SALTS OF HEMATOPORHYRINE AND DERIVATIVES THEREOF, METHOD OF PREPARING COMPLEX SALTS, METHOD OF PREPARING MIXTURE OF COMPLEX SALTS, AND PHARMACEUTICAL COMPOSITION
摘要 FIELD: chemical industry. SUBSTANCE: complex salts of hematoporthyrine and derivatives thereof of formula 1: <EMI ID=0.96 HE=63 WI=90 TI=CHI> wherein R and R are the same or different and are -CH=CH<SB>2</SB>, -CH/OH/CH<SB>3</SB> and -CH/OR<SP>3</SP>/CH<SB>3</SB>, wherein R is group forming oligomer containing ether or ester bonds having from 1 to 5 identical or different units, either R and R are CHR<SP>4</SP>CH<SB>3</SB>; A is main amino acid; m= 2-4 and n=1-5. Compounds I are useful as agent for detecting and treating malignant tumors. EFFECT: improved properties of the pharmaceutical composition. 13 cl, 6 dwg, 26 ex, 4 tbl_
申请公布号 RU2122003(C1) 申请公布日期 1998.11.20
申请号 RU19920004314 申请日期 1992.10.28
申请人 VOJSKOVA AKADEMIJA TEKHNICHNA IM.JAROSLAVA DABROVS 发明人 AL'FREDA GRACHYK;EZHI KONARSKI
分类号 A61K31/40;A61K31/555;A61K41/00;A61K49/00;C07C229/26;C07C279/14;C07D207/30;C07D207/44;C07D233/64;C07D257/00;C07D487/22;C07D519/00 主分类号 A61K31/40
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