| 发明名称 |
METHODS OF TREATMENT USING NBS-1, ANTIBODIES AND PROTEINS THERETO, AND USES OF THE ANTIBODIES |
| 摘要 |
Antibodies that will specifically bind to NBS-1 are described. It is also shown that NBS-1 will interact with p53 responsive elements in a p53 promoter. Thus, NBS-1 can be used in subjects having a p53-dependent tumor to inhibit growth of that tumor.
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| 申请公布号 |
WO9851350(A1) |
申请公布日期 |
1998.11.19 |
| 申请号 |
WO1998US09516 |
申请日期 |
1998.05.12 |
| 申请人 |
DANA-FARBER CANCER INSTITUTE |
发明人 |
KAELIN, WILLIAM;JOST, CHRISTINE |
| 分类号 |
C07K14/47;C07K16/18;(IPC1-7):A61K48/00;C07K16/32;G01N33/68;G01N33/577 |
主分类号 |
C07K14/47 |
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