NEW PROCESS FOR THE PREPARATION OF AZITHROMYCIN

摘要

The present invention describes a new process for the preparation of azithromyci n from a suitable imino ether as precursor, characterised by the fact that the red uction and the reductive methylation of said imino ether are sequentially carried out w ith a noble metal catalyst and hydrogen in the presence of formaldehyde, or a source thereof, wherein both reactions can be conducted in the same reaction vessel.