| 摘要 |
<p>A molecular characterization detector for detecting fluctuation in scattered light intensity from molecules in a liquid sample includes a scattering cell (10), a semiconductor laser (20) for directing a light beam (22) through the scattering cell (10) along an optical axis (24) so that the light beam is scattered by molecules of the sample and produces scattered light, and a detector assembly (50) including an avalanche photodetector (80) for detecting fluctuations in intensity of the scattered light in a direction perpendicular to the optical axis (24). The molecular characterization detector (50) may be incorporated into an instrument for measuring hydrodynamic radius of molecules. The instrument includes the molecular characterization detector, a correlator (200) for determining a correlation function representative of a characteristic decay time of the fluctuations in the scattered light intensity and a processor (240) for determining hydrodynamic radius of the sample molecules from the correlation function.</p> |
