摘要 |
<p>A transport matrix and diagnostic device are provided which produce a physically detectable change in a predetermined distribution across a detection zone which correlates with the amount of selected analyte in a sample. The matrix includes detection zones (26 and 28) having a capture reagent yielding a physically detectable change which correlates with the amount of selected analyte in a sample. The detection zone has a leading boundary (100) which first encounters the sample and a trailing boundary (102) which encounters the sample after being transported across the detection zone. The capture reagent is immobilized on the matrix in a predetermined distribution from the leading boundary to the trailing boundary of the detection zone. A method is also provided which determines the level of a selected analyte in a predetermined pattern across a detection zone on a transport matrix which correlates with the amount of selected analyte.</p> |