发明名称 |
Arzneizusammensetzungen enthaltend Nanokapseln |
摘要 |
Pharmaceutical composition in the form of a colloidal suspension of nanocapsules which comprises an oily phase consisting essentially of an oil containing, in solution, a surface-active agent and, in suspension, nanocapsules having a diameter of less than 500 nanometers, including an aqueous phase consisting essentially of a solution or a suspension of a substance of therapeutic activity, a surface-active agent and optionally ethanol, as well as a process for the preparation of this composition. The walls of the said nanocapsules are formed of a poly(alkyl 2-cyanoacrylate) the alkyl radical of which includes from 1 to 6 carbon atoms. This composition is advantageously suitable for the oral administration of polypeptides and polysaccharides. |
申请公布号 |
DE69413857(D1) |
申请公布日期 |
1998.11.19 |
申请号 |
DE1994613857 |
申请日期 |
1994.01.05 |
申请人 |
UCB S.A., BRUESSEL/BRUXELLES, BE |
发明人 |
VRANCKX, HENRI, B-1190 BRUXELLES, BE;DEMOUSTIER, MARTINE, B-1080 BRUXELLES, BE;DELEERS, MICHEL, B-1630 LINKEBEEK, BE |
分类号 |
A61K38/28;A61K9/51;A61K31/715;A61K31/727;A61K38/04;A61K38/23;A61K47/32;B01J13/14;B01J13/18;(IPC1-7):A61K9/51 |
主分类号 |
A61K38/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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