发明名称 |
VERFAHREN ZUR HERSTELLUNG VON N-ACETYL-NEURAMINSÄUREDERIVATEN |
摘要 |
<p>PCT No. PCT/EP94/01940 Sec. 371 Date Mar. 8, 1996 Sec. 102(e) Date Mar. 8, 1996 PCT Filed Jun. 15, 1994 PCT Pub. No. WO95/00503 PCT Pub. Date Jan. 5, 1995The invention provides a method for the preparation of the compound of formula(I) <IMAGE> (I) which comprises catalytic hydrogenolysis of a compound of formula (II) <IMAGE> (II) (wherein R is H or a C1-4alkyl group and R1 is H or a hydroxyl protecting group for example an acyl group such as acetyl) in aqueous formic acid followed, where necessary, by hydrolysis.</p> |
申请公布号 |
DE69413974(D1) |
申请公布日期 |
1998.11.19 |
申请号 |
DE1994613974 |
申请日期 |
1994.06.15 |
申请人 |
BIOTA SCIENTIFIC MANAGEMENT PTY. LTD., MELBOURNE, VICTORIA, AU |
发明人 |
SEARLE, ANDREW, DAVID GLAXO RESEARCH AND, MIDDLESEX UB6 0HE, GB;WILLIAMSON, CHRISTOPHER GLAXO RESEARCH AND, MIDDLESEX UB6 0HE, GB |
分类号 |
B01J23/44;B01J23/62;C07B61/00;C07D309/28;(IPC1-7):C07D309/28 |
主分类号 |
B01J23/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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