发明名称 |
METHOD OF MAKING MICROENCAPSULATED DNA FOR VACCINATION AND GENE THERAPY |
摘要 |
<p>A method of making a microparticle that contains DNA coding for a polypeptide is described in which a solvent extraction method is used and solvent extraction takes place at elevated temperature. Oral administration of the microparticle leads to its expression. DNA coding for an immunogen is for stimulating antibody formation in a recipient and DNA coding for a nonimmunogenic polypeptide is for gene therapy applications. DNA is incorporated into the microparticle without destruction of its function.</p> |
申请公布号 |
CA2289761(A1) |
申请公布日期 |
1998.11.19 |
申请号 |
CA19982289761 |
申请日期 |
1998.05.15 |
申请人 |
MICROBIOLOGICAL RESEARCH AUTHORITY |
发明人 |
FARRAR, GRAHAM HENRY;CLEGG, JAMES CHRISTOPHER STEPHEN;JONES, DAVID HUGH |
分类号 |
C12N15/09;A61K9/00;A61K9/16;A61K9/50;A61K9/66;A61K31/70;A61K31/711;A61K39/15;A61K39/165;A61K48/00;C12N15/88;(IPC1-7):A61K9/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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