发明名称 |
SUPPRESSION OF TUMOR NECROSIS FACTOR ALPHA AND VASCULAR ENDOTHELIAL GROWTH FACTOR IN THERAPY |
摘要 |
Methods for treating and/or preventing a TNF-mediated disease in an individual are disclosed. Also disclosed are compositions comprising a TNF alpha antagonist and a VEGF antagonist. TNF-mediated diseases include rheumatoid arthritis, Crohn's disease, and acute and chronic immune diseases associated with transplantation.
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申请公布号 |
WO9851344(A1) |
申请公布日期 |
1998.11.19 |
申请号 |
WO1998GB01343 |
申请日期 |
1998.05.12 |
申请人 |
THE KENNEDY INSTITUTE OF RHEUMATOLOGY |
发明人 |
FELDMANN, MARC;MAINI, RAVINDER, NATH;PALEOLOG, EWA, MARIA |
分类号 |
A61K45/06;A61K31/00;A61K31/454;A61K31/505;A61K38/00;A61K39/395;A61P29/00;A61P37/00;A61P37/02;A61P43/00;C07K16/24;(IPC1-7):A61K39/395;A61K38/17 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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