| 摘要 |
PROBLEM TO BE SOLVED: To form the array structure of a reagent spot easily by allowing a combined reagent to contact, for a sufficient amount of time, the solid phase region of metal and oxidation metal so that their adsorption combination type formation can be formed. SOLUTION: A gold layer that is approximately 50 nm thick is deposited in a high vacuum on a glass support 10, the support 10 is fixed on an XYZ table 2 with a pump 4 immediately after the deposition, and a micro-liter plate 6 is mounted to a working surface. To form a reagent spot on a metal surface, the tip of the pump 4 is dipped into a corresponding liquid and a liquid drip 8 with a capacity of approximately 1 nl is placed at a specific position on the surface. After the pump 4 is washed for two times in a pure solvent, the liquid drip 8 of a next solution is placed at a next specific spot and the process is repeated successively as needed. Then, a gold surface where the reagent spot is placed is hardened for approximately 10 minutes. In the meantime, self-assembled single layer is formed on a surface that is covered with the liquid drip 8. A non-adsorption molecule is washed in a pure solvent, thus quickly manufacturing a surface with a reaction spot being demarcated spatially.
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