发明名称 |
Drug release stent coating process |
摘要 |
A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologically active species, possibly of controlled average particle size, to form a coating on each stent surface. The coatings are cured in situ and the coated, cured prosthesis are sterilized in a step that includes preferred pretreatment with argon gas plasma and exposure to gamma radiation electron beam, ethylene oxide, steam. |
申请公布号 |
US5837313(A) |
申请公布日期 |
1998.11.17 |
申请号 |
US19960663490 |
申请日期 |
1996.06.13 |
申请人 |
SCHNEIDER (USA) INC |
发明人 |
DING, NI;HELMUS, MICHAEL N. |
分类号 |
A61F2/82;A61F;A61F2/00;A61F2/06;A61F2/86;A61F2/90;A61K9/00;A61L;A61L27/22;A61L31/00;A61L31/10;A61L31/14;A61L31/16;A61L33/00;(IPC1-7):B05D3/00;A61L27/00 |
主分类号 |
A61F2/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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