发明名称 N-acyl-alpha aminoacids derivatives
摘要 <p>N-Aroyl- alpha -aminocarboxylic acid derivatives of the formula <IMAGE> in which L, R' to R''' and Q have the meaning given in the description, can be used for the treatment or prophylaxis of diseases which are caused by the binding of adhesive proteins to blood platelets, as well as by blood platelet aggregation and cell-cell adhesion. They are prepared by removing protective groups in appropriately protected compounds or by conversion of the cyano group to the amidino group in appropriate nitriles.</p>
申请公布号 HK1003997(A1) 申请公布日期 1998.11.13
申请号 HK19980103232 申请日期 1998.04.17
申请人 F. HOFFMANN-LA ROCHE AG 发明人 LEO ALIG;PAUL HADVARY;MARIANNE HURZELER;MARCEL MULLER;BEAT STEINER;THOMAS WELLER
分类号 A61K31/155;A61K;A61K31/165;A61K31/195;A61K31/198;A61K31/445;A61K31/451;A61P7/02;A61P7/04;C07C227/00;C07C229/00;C07C229/10;C07C233/76;C07C237/22;C07C257/18;C07C279/18;C07D;C07D207/08;C07D207/12;C07D207/16;C07D211/22;C07D211/40;C07D211/42;C07D211/44;C07D211/46;C07D211/48;C07D211/52;C07D401/06;C07D401/12;C07D451/06;C07D453/06;(IPC1-7):C07D 主分类号 A61K31/155
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