There are provided novel compounds of formula (I) wherein R<1> represents a 2-thienyl or 3-thienyl ring and R<2> represents C 1 to 4 alkyl and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are selective inhibitors of the neuronal isoform of nitric oxid synthase.
申请公布号
WO9850380(A1)
申请公布日期
1998.11.12
申请号
WO1998SE00792
申请日期
1998.04.28
申请人
ASTRA AKTIEBOLAG;MACDONALD, JAMES;MATZ, JAMES;SHAKESPEARE, WILLIAM