| 发明名称 |
Recombinant YF virus vaccines recovered from the infectious cDNA |
| 摘要 |
<p>The present invention is related to a vaccine composition for humans against YF infections consisting essencially of a recombinant YF virus, YFiv5.2/DD, which is regenerated from YF infectious cDNA. There is provided new plasmids, pYF 5'3' IV/G1/2 and pYFM 5.2/T3/27, which together, have the complete sequence of said YF infectious cDNA. The method for producing recombinant YF virus and the Original, Primary and Secondary Seed Lots are other embodiments of the present invention. <IMAGE></p> |
| 申请公布号 |
EP0877086(A2) |
申请公布日期 |
1998.11.11 |
| 申请号 |
EP19980106495 |
申请日期 |
1998.04.08 |
| 申请人 |
FUNDACAO OSWALDO CRUZ (FIOCRUZ) |
发明人 |
GALLER, RICARDO;DA SILVA FREIRE, MARCOS |
| 分类号 |
A61K39/12;A61K39/00;C07K14/18;C12N7/00;C12N7/01;C12N15/40;(IPC1-7):C12N15/40 |
主分类号 |
A61K39/12 |
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