发明名称 |
Method of treating chronic progressive vascular scarring diseases |
摘要 |
A method of treating a mammalian patient suffering from a chronic progressive vascular scarring disease (CPVSD), particularly arteriosclerotic diseases such as atherosclerosis, to halt or at least slow substantially the progress of the disease and cause resolution and/or diminution of already-formed scarring and lesions. The method consists of the administration to the patient of a pharmaceutical composition containing an effective amount of pentosan polysulfate (PPS) or a pharmaceutically acceptable salt thereof. The oral route of administration is preferred, with the total daily dosage of PPS or PPS salt ranging from about 5 to about 30 mg/kg of patient body weight, or about 350 to about 2,000 mg per day in adult human patients. |
申请公布号 |
AU7248298(A) |
申请公布日期 |
1998.11.11 |
申请号 |
AU19980072482 |
申请日期 |
1998.04.10 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, |
发明人 |
GARY E STRIKER;LILIANE J STRIKER |
分类号 |
A61K9/48;A61K31/715;A61K31/737;A61K47/12;A61K47/38;A61P9/00;A61P9/10;A61P13/02;A61P15/00;A61P27/02;C08B37/00 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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