发明名称 NOVEL DERIVATIVES OF NAPHTHYLPIPERAZINE
摘要 <p>A description is given of new naphthylpiperazine derivatives of general formula (I) <CHEM> in which R1 and R2, equal to or different from each other, can be hydrogen, a short chain alkyl group, halogen, a nitro group, an amino group, an acylamino group and a short chain alkoxy group; n can take values between 2 and 5; and R3 can be a methoxyl radical, a fluorine and a hydrogen atom, and their addition salts with pharmaceutically acceptable acids. The compounds present affinity for serotonin 5HT1A and 5HT2 receptors and for dopamine D2 receptors, and can be useful as antipsychotics. Their preparation is also described.</p>
申请公布号 CZ9801118(A3) 申请公布日期 1998.11.11
申请号 CZ19980001118 申请日期 1998.04.10
申请人 FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS 发明人 ORJALES-VENERO AURELIO;GARCIA-DOMINGUEZ NEFTALI
分类号 C07D401/06;A61K31/495;A61K31/50;A61K31/502;A61P25/18;A61P43/00;C07D237/32;(IPC1-7):C07D401/06 主分类号 C07D401/06
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