| 摘要 |
PCT No. PCT/GB94/01847 Sec. 371 Date Feb. 13, 1996 Sec. 102(e) Date Feb. 13, 1996 PCT Filed Aug. 24, 1994 PCT Pub. No. WO95/05818 PCT Pub. Date Mar. 2, 1995Compounds of formula (I) are usefully employed in pharmaceutical compositions either in a mixture or in association with a pharmaceutically acceptable carrier or diluent; <IMAGE> formula I wherein M is a diamagnetic metal atom or a diamagnetic metal compound of silicon or a compound of silicon or is 2H; one H being bonded to each of the two nitrogen atoms depicted as being bonded to M (positions 29 and 31 shown); R1 to R25 are the same or different and are independently selected from C1-C20 alkyl, C2-C20 alkenyl, X-O-Y, (a), X2COOX1, X2CONR1R11 and H; wherein X and X2 are independently selected from a chemical bond, -(CH2)n- where n is an integer from 1 to 20 and -(CH2)aCH=CH(CH2)b where a and b are independently selected from integers 0-20 and a+b totals from 0 to 20; X1 is independently selected from C1-20 alkyl, C2-20 alkenyl and H, R1 and R11 are independently selected from H, C1-20 alkyl, C2-20 alkenyl, -(CH2)n; Y is independently selected from C1-20 alkyl, C2-20 alkenyl and H; provided that not all R1-R25 are simultaneously H. The compounds of formula (I) may also be used for the preparation of a medicament for photodynamic therapy.
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