发明名称 |
Magnetic resonance imaging |
摘要 |
The invention provides a method of monitoring the vasodilatory or vasoconstrictive effects of a physiologically active substance administered to a human or non-human animal body, said method comprising the steps of: administering said substance into said body; administering into the systemic vasculature of said body a contrast enhancing amount of an intravascular paramagnetic metal containing magnetic resonance imaging contrast agent; subjecting said body to a magnetic resonance imaging procedure capable of generating from magnetic resonance signals from said body a series of temporally spaced images of at least a part of said body into which said agent passes, said procedure being a fast imaging procedure having an image acquisition time of less than five seconds; and detecting temporal variations in said signals or images whereby to monitor the vasoconstriction or vasodilation induced by said substance.
|
申请公布号 |
US5833947(A) |
申请公布日期 |
1998.11.10 |
申请号 |
US19960604778 |
申请日期 |
1996.02.23 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ROCKLAGE, SCOTT M.;KUCHARCZYK, JOHN;MOSELEY, MICHAEL E. |
分类号 |
A61K49/06;G01R33/28;G01R33/465;G01R33/561;G01R33/563;(IPC1-7):A61B5/055 |
主分类号 |
A61K49/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|