Production of heterologous peptides

摘要

PCT No. PCT/GB94/01789 Sec. 371 Date Feb. 13, 1996 Sec. 102(e) Date Feb. 13, 1996 PCT Filed Aug. 15, 1994 PCT Pub. No. WO95/05474 PCT Pub. Date Feb. 23, 1995The invention relates to a method and recombinant means for engineering the production of heterologous peptides in filamentous fungus. The invention involves the genetic manipulation of the glucoamylase gene in order to provide a restriction site in same so that the promoter sequence of the glucoamylase gene can be coupled to a sequence encoding a heterologous peptide whereby the production of the peptide will be under the control of the promoter sequence of the glucoamylase gene.