MIXTURE HAVING ANTITUMOR ACTIVITIES

摘要

A purified hot-water extract from Mycobacterium bovis (BCG vaccine) has been found to have significant antitumor activity against a mouse bladder tumor model and a murine sarcoma in vivo, but not in vitro. The material, termed PS1A1, has an approximate molecular weight of between 60 and 90 kDa, is freely soluble in wate r, but has low solubility in acetone or ethanol, and is remarkably heat-stable.