| 发明名称 |
Adeno-associated viral (AAV) liposomes and methods related thereto |
| 摘要 |
A composition for genetic manipulation which comprises a liposome comprised of lipid material, and adeno-associated viral (AAV) material. Typically, the AAV material is plasmid, and comprises a terminal repeat of the AAV genome. Methods are disclosed for introducing genetic material into cells by use of AAV liposomes. Accordingly, genetic material was introduced and integrated into stem cells, T cells, primary tumor cells, or tumor cell lines.
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| 申请公布号 |
US5834441(A) |
申请公布日期 |
1998.11.10 |
| 申请号 |
US19940305221 |
申请日期 |
1994.09.12 |
| 申请人 |
RHONE-POULENC RORER PHARMACEUTICALS INC. |
发明人 |
PHILIP, RAMILA;LEBKOWSKI, JANE |
| 分类号 |
C12N15/09;A61K9/127;A61K31/70;A61K35/12;A61K38/00;A61K38/45;A61K38/46;A61K47/48;A61K48/00;A61P31/12;A61P35/00;A61P37/00;A61P37/04;C07H21/04;C07K14/55;C12N5/10;C12N15/11;C12N15/12;C12N15/86;C12N15/864;C12N15/88;(IPC1-7):A01N63/00;C12N5/00 |
主分类号 |
C12N15/09 |
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