摘要 |
PROBLEM TO BE SOLVED: To obtain a telomerase activity reducer excellent in safety, capable of effectively reducing telomerase. SOLUTION: This telomerase activity reducer comprises a substance selected from the group consisting of 9-fluoro-2,3-dihydro 3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-7H-pyrido[1,2,3-de] [1,4] benzoxazine-6-carboxylic acid, its optically active substance, a pharmacologically permissible salt and its hydrate as an active ingredient. |