| 摘要 |
PCT No. PCT/GB92/02348 Sec. 371 Date Jun. 15, 1994 Sec. 102(e) Date Jun. 15, 1994 PCT Filed Dec. 17, 1992 PCT Pub. No. WO93/11738 PCT Pub. Date Jun. 24, 1993A dentifrice formulation provides a composition which contains and antibacterially effective amount of a lanthocin-type bacyeriocin antibacterial agent such as nisin, gramicidin, or tyrothicin and an orally acceptable low anion or anio-free excipient mixture containing a purified surfactant selected from nonionic surfactant, cationic surfactant and amphoteric surfactant so as to avoid anionic surfactant; a low or anion or anion-free abrasive; a nonionic thickening agent; a humectant; and a fluoride ion producing compound.
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